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Yes, it certainly looks like Sansom's mark. The Sheffield crown changed shape in 1860 and the Victoria duty mark was first used in 1840. So that tightens the possible date range to 1840-1859. I have, so far, only seen Sansom's mark with hallmarks dated 1835 to 1841 so it seems very likely that your knife handle dates from the first part of the 1840-1859 range.